Nursing News

Drug-resistant infections: If you can't beat 'em, starve 'em, scientists find

  • Researchers repurpose drug to deny drug-resistant fungus of iron, an element crucial to its survival

BUFFALO, N.Y., USA (May 24, 2019) -- How do you fight a fungal infection that is becoming increasingly resistant to medicine? By starving it, found a team of University at Buffalo and Temple University researchers. To treat Candida albicans, a common yeast that can cause illness in those with weakened immune systems, researchers limited the fungus' access to iron, an element crucial to the organism's survival.

Psychiatry

Study supports effectiveness of new fast-acting antidepressant, esketamine nasal spray

Washington, DC, USA (May 21, 2019) - New research supports the effectiveness and safety of esketamine nasal spray in treating depression in people who have not responded to previous treatment. The research will be published online today in the American Journal of Psychiatry. This study is one of the key studies that led to the recent Food and Drug Administration (FDA) approval of esketamine nasal spray, in conjunction with an oral antidepressant, for use in people with treatment-resistant depression.

Implementing a care pathway for spatial neglect to improve stroke outcomes

  • Stroke researchers strive to close the implementation gap for spatial neglect care

East Hanover, NJ., USA (May 14, 2019) - Spatial neglect remains a hidden disability despite the availability of effective tools for the diagnosis and treatment for this common complication of stroke. Addressing this implementation gap is critical to reducing disability, improving outcomes and controlling costs of stroke care, according to an article in Current Neurology and Neuroscience Reports, "Update on the Clinical Approach to Spatial Neglect" (DOI:10.1007/s11910-019-0940-0) published online on April 4, 2019. The authors are A.M. Barrett, MD, of the Center for Stroke Rehabilitation Research at Kessler Foundation, and K.E. Houston, OD, MSc, of Harvard Medical School and Spaulding Rehabilitation Hospital.

Findings can be used to develop new, health-focused interventions in aging populations

Physical and mental health of seniors linked to optimism, wisdom and loneliness

San Diego, California, USA (May 8, 2019) -- Ten thousand Baby Boomers turn 65 every day. By 2029, the entire generation born between 1946 and 1964 will be at least that old. What happens next concerns millions of Americans. Advancing age is broadly associated with declining cognitive, physical and mental health. In a new study of older adults living independently in a senior continuing care facility, researchers at University of California San Diego School of Medicine analyzed how distinctive factors, such as wisdom, loneliness, income and sleep quality, impact -- for good and bad -- the physical and mental functioning of older persons.

When doctors and nurses can disclose and discuss errors, hospital mortality rates decline

Bocconi, Italy (May 7, 2019) - An association between hospitals' openness and mortality rates has been demonstrated for the first time in a study among 137 acute trusts in England, published yesterday in the May issue of Health Affairs. The diffusion of a culture of openness in hospitals is associated with lower hospital mortality, according to a study conducted among 137 acute trusts in England by Veronica Toffolutti (Bocconi University and London School of Hygiene & Tropical Medicine) and David Stuckler (Bocconi University) published in Health Affairs.

Prolonged exposure to low-dose radiation may increase the risk of hypertension, a known cause of heart disease and stroke

DALLAS, USA (May 3, 2019) - Prolonged exposure to low doses of ionizing radiation increased the risk of hypertension, according to a study of workers at a nuclear plant in Russia published in the American Heart Association's journal Hypertension. Uncontrolled hypertension, also known as high blood pressure, can to lead to heart attack, stroke, heart failure and other serious health problems.

Simple positive emotion skills yield benefits in physical and emotional health

Teaching happiness to dementia caregivers reduces their depression, anxiety

CHICAGO, ILL, USA (May 2, 2019) - Caring for family members with dementia -- which is on the rise in the U.S. -- causes significant emotional and physical stress that increases caregivers' risk of depression, anxiety and death.  A new method of coping with that stress by teaching people how to focus on positive emotions reduced their anxiety and depression after six weeks, reports a new national Northwestern Medicine study. It also resulted in better self-reported physical health and positive attitudes toward caregiving.

A third of type one diabetes is misdiagnosed in the over 30s

Exeter (April 30, 2019) - More than a third of people over the age of 30 who are initially diagnosed with type 2 diabetes actually have type 1, meaning they are not receiving the right treatment, new research has revealed. The study, led by the University of Exeter, shows that 38% of patients with type 1 diabetes occurring after age 30 were initially treated as type 2 diabetes (without insulin). the team found that half of those misdiagnosed were still diagnosed as type 2 diabetes 13 years later.

Biomarker for chronic fatigue syndrome identified by Stanford researchers

Stanford, California USA (April 29, 2019) - People suffering from a debilitating and often discounted disease known as chronic fatigue syndrome may soon have something they've been seeking for decades: scientific proof of their ailment. Researchers at the Stanford University School of Medicine have created a blood test that can flag the disease, which currently lacks a standard, reliable diagnostic test.

Pediatricians and nurse practitioners report using strategies to improve HPV vaccination

BALTIMORE, USA(April 27, 2019) - Pediatricians and nurse practitioners report using several strategies to improve human papillomavirus (HPV) vaccination, yet also perceive barriers, according to a national American Academy of Pediatrics (AAP) Pediatric Research in Office Settings (PROS) network study. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2019 Meeting, taking place on April 24 - May 1 in Baltimore.

As numbers of opioid exposed newborns have increased throughout the US, many approaches have been used to improve care of these infants

Eat, sleep and console tool decreases length of stay and post natal use of opiates

BALTIMORE, USA (April 27, 2019) - A new quality improvement tool called Eat, Sleep and Console (ESC) shows consistent signs of improved care of opioid-exposed newborns in neonatal intensive care units (NICUs). Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2019 Meeting, taking place on April 24 - May 1 in Baltimore.

How does chronic edema impact health-related quality of life?

New Rochelle, NY, USA(April 26, 2019) -- Final results of the large, international LIMPRINT study have provided new data on the prevalence of chronic swelling and the devastating impact it can have on health-related quality of life. A broad range of articles that give a comprehensive view of the conceptual design, implementation, results, and interpretation of the LIMPRINT findings are published in a special issue of Lymphatic Research and Biology, a peer-reviewed online journal from Mary Ann Liebert, Inc., publishers. Click here to read the open access special issue on the Lymphatic Research and Biology website.

Accidentally dislodged breathing tube is fourth-most common adverse event in the nation's NICUs

Children's NICU slashes unintended extubation rates by 60% over 10 years

WASHINGTON, USA-(April 26, 2019) - A quality-improvement project at the neonatal intensive care unit (NICU) at Children's National that included standardized taping methods, bedside review of events within 72 hours and reducing how often newborns received chest X-rays reduced unintended extubations by 60% over 10 years and saved an estimated $1.5 million per year, according to research published online April 26, 2019 in Pediatrics.

Stroke Journal Report

Many stroke patients not screened for osteoporosis, despite known risks

DALLAS, USA (April 25, 2019) -- The majority of stroke survivors are not screened or treated for osteoporosis, broken bones, or fall risk -- despite stroke being a risk factor for these conditions. The risk is up to four times greater than in healthy people, according to new research in the American Heart Association's journal Stroke.

Alcohol relapse rate among liver transplant recipients identical regardless of sobriety period

Baltimore, Maryland, USA (April 25, 2019) - For decades, patients with liver disease related to alcohol use have been told they must be sober for six months before they can get a liver transplant. Many die before that six-month wait period is up. Now, a growing number of researchers are questioning that six-month waiting period.

A correlation was found between strong feelings of responsibility and likelihood of developing OCD or GAD in American university students

Being too harsh on yourself could lead to OCD and anxiety

Hiroshima, Japan (April 25 2019) - A new study has found that people who reported intense feelings of responsibility were susceptible to developing Obsessive Compulsive Disorder (OCD) or Generalized Anxiety Disorder (GAD) was published in the International Journal of Cognitive Therapy.

The vaccine proves safe in a small sample of human subjects, opening the way for the next phase of testing

Novel vaccine for colorectal cancer shows positive phase I results

PHILADELPHIA, USA (April 25, 2019) -- A new colorectal cancer vaccine showed positive results in the phase 1 clinical trial to demonstrate that the approach is safe. The patients treated had no signs of serious adverse events and samples of their blood contained markers of immune activation -- an early indication that the vaccine could activate immune cells to fight colorectal tumors and metastases. Further tests to determine if the vaccine is effective at slowing tumor growth are forthcoming.

The glass half-full: How optimism can bias prognosis in serious illness

Burlington, Vermont, USA (April 25, 2019) - Most people think of optimism as a good thing - a positive outlook in challenging circumstances. But in reality, it's a psychological state that can be "contagious" in a bad way. A new study, published in the journal Psycho-Oncology, details how a seriously ill patient's optimism can impact a clinician's survival prognosis in palliative care conversations.

Dentists can be the first line of defense against domestic violence

PHOENIX, USA (April 25, 2019) - The University of Arizona College of Medicine - Phoenix and Midwestern University have published an article to bring to light the important role dentists can play in identifying domestic violence victims. Published April 11 in the Journal of Aggression, Maltreatment and Trauma, the article reports that as much as 75 percent of head and neck trauma associated with domestic violence occurs with oral injury. Researchers concluded that dentists are in the unique position to be the first line of defense in identifying evidence of assault, and then reporting potential cases of domestic violence.

'Cook your Wash' campaign reduces risk of HIV transmission

Researchers verify new method of HIV transmission among injection drug users and effective prevention technique

LONDON, ON, CANADA (April 25, 2019) - New studies from Lawson Health Research Institute and Western University have found for the first time that HIV can be transmitted through the sharing of equipment used to prepare drugs before injection and that a simple intervention - heating the equipment with a cigarette lighter for 10 seconds - can destroy the HIV virus, preventing that transmission. The findings, used to inform a public health campaign called 'Cook Your Wash,' have helped reduce rates of HIV transmission in London, Ontario.

New clinical review provides the most comprehensive treatment guidelines for severe atopic dermatitis (eczema): 

Researchers raise bar for successful management of severe atopic dermatitis

AURORA, Colorado, USA (Jan. 15, 2019) - A team of investigators from the University of Colorado College of Nursing at CU Anschutz Medical Campus and National Jewish Health has identified comprehensive guidelines for managing severe atopic dermatitis (AD), the most common form of eczema. The clinical management review was recently published in The Journal of Allergy and Clinical Immunology: In Practice.

Discovery opens doors to improving diagnostics and developing new therapy for majority of ALS patients

Harvard research reveals potential therapeutic target for ALS

Cambridge, MA, USA (January 15, 2019) - Research led by stem cell scientists at Harvard University points to a potential new biomarker and drug target for amyotrophic lateral sclerosis (ALS), a neurological disease that is extremely difficult to diagnose and treat. Published in Nature Neuroscience, the study used stem cell models of human motor neurons to reveal the gene STMN2 as a potential therapeutic target, demonstrating the value of this human stem cell model approach in drug discovery.

Evaluating surgeon gowning steps for optimal sterile operating room techniques

January 4, 2019 - For surgeons getting ready to enter the operating room (OR), the chances of contamination may be lower if they put their gowns on by themselves - without the assistance of a surgical technician, according to an experimental study in the Journal of Orthopaedic Trauma. The journal is published in the Lippincott portfolio by Wolters Kluwer.

Contamination occurs in most two-person assisted gowning procedures, suggests the study by Kenton Panas, MD, and colleagues of The University of Oklahoma Health Sciences Center, Oklahoma City. The researchers write, "We suggest a single-person gowning step to help optimize sterile technique in the OR.".

The greater the hearing loss, the greater the risk of having symptoms of depression, finds study of elderly Hispanics

To head off late-life depression, check your hearing

New York, NY, USA (January 2, 2019) -- A new study found that elderly individuals with age-related hearing loss had more symptoms of depression; the greater the hearing loss, the greater the risk of having depressive symptoms. The findings suggest that treatment of age-related hearing loss, which is underrecognized and undertreated among all elderly, could be one way to head off late-life depression. The study was published online in JAMA Otolaryngology-Head & Neck Surgery.

Study confirms one hour rule

After naloxone, when can opioid overdose patients be safely discharged?

BUFFALO, N.Y., USA (December 28, 2018) -- Naloxone has saved thousands of lives. But can patients be safely discharged from the Emergency Department (ED) just an hour after they receive the medication that curtails drug overdoses? According to the St. Paul's Early Discharge Rule developed in 2000, that's how long providers should observe patients after naloxone treatment, so long as their vital signs meet specific criteria and they are ambulatory.
But the rule was never externally validated or assessed in light of the changes that have occurred in recent years with opioid use disorder. That's why University at Buffalo researchers conducted the current study, published today in Academic Emergency Medicine, and the first to clinically assess the rule developed at St. Paul's Hospital in Vancouver.

New pathways for implementing universal suicide risk screening in healthcare settings

  • Model could help hospitals better identify and aid youth at risk for suicide

Bethesda, MD, USA (December 20, 2018) -- A new report, authored in part by researchers at the National Institute of Mental Health (NIMH), part of the National Institutes of Health, provides guidance on how to implement universal suicide risk screening of youth in medical settings. The report describes a way for hospitals to address the rising suicide rate in a way that is flexible and mindful of limited resources.

Research finds opioids may help chronic pain, a little

  • Should not be first line therapy for chronic non-cancer pain

Hamilton, ON, USA (October 18, 2018) - Use of opioids for patients with chronic, non-cancer pain may help, but not a lot. In a study published today by the Journal of the American Medical Association (JAMA), McMaster University researchers reviewed 96 clinical trials with more than 26,000 participants and found opioids provide only small improvements in pain, physical functioning and sleep quality compared to a placebo.

Study examines effects of taking ondansetron during first trimester of pregnancy

  • No increased risk of cardiac malformations, slight increased risk of oral clefts associated with common anti-nausea medication


Boston, MA, USA (December 18, 2018) -- Ondansetron (Zofran) is commonly and increasingly prescribed during pregnancy to relieve nausea. In 2014, an estimated 22 percent of pregnant women in the U.S. had used the drug at some point during their pregnancy. Despite its prevalence, data on the safety of the drug and any effects on the developing fetus have been limited, with small-scale studies producing conflicting results. A new study conducted by investigators at Brigham and Women's Hospital has analyzed data from more than 88,000 pregnancies in which pregnant women had taken ondansetron during the first trimester to examine risk of cardiac malformations or oral clefts. In a paper published online in JAMA, the team reports no increased risk of cardiac malformations and a very small increased risk of oral clefts.

A study from the Swedish dementia registry

Correlation of stroke and dementia with death

Soest, The Netherlands (December 14, 2018) - A great number of studies have consistently scrutinized the relation between dementia and stroke, with a multiple fold increase in the risk factor for death. Swedish scientists at Karolinska Institute, conducted a retrospective survey using patient data in the Swedish Dementia Registry to figure out such relationships through direct association of dementia and ischemic stroke (IS) deaths. Additionally, other recorded evidences e.g. cause of death, any co-occurring disease as well as use of different drugs had been obtained from Swedish nationwide health registers.

Pulling off a Band-Aid may soon get a lot less painful

A painless adhesive

  • Adhesives for biomedical applications can be detached with light

Cambridge, MA, USA (December 14, 2018) - Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) and Xi'an Jiaotong University in China have developed a new type of adhesive that can strongly adhere wet materials -- such as hydrogel and living tissue -- and be easily detached with a specific frequency of light.

Study shows

Prevention, treatment of ICU acquired delirium requires personalized approach

INDIANAPOLIS, Indiana, USA (December 13, 2018) - A population heath study from the Regenstrief Institute and Indiana University Center for Aging Research has determined that haloperidol, the drug most commonly used to treat delirium in hospital medical and surgical intensive care units (ICUs), did not benefit elective thoracic surgery ICU patients when given prophylactically, with the possible exception of those who have had surgery to remove their esophagus. The study results indicate the need for a personalized approach to delirium in the ICU.

replace biopsyNovel technique may significantly reduce breast biopsies

OAK BROOK, Ill., USA (December 11, 2018)  - A novel technique that uses mammography to determine the biological tissue composition of a tumor could help reduce unnecessary breast biopsies, according to a new study appearing in the journal Radiology. Mammography has been effective at reducing deaths from breast cancer by detecting cancers in their earliest, most treatable stages. However, many women are called back for additional diagnostic imaging and, in many cases, biopsies, for abnormal findings that are ultimately proven benign. Research estimates this recall rate to be more than 10 percent in the United States.

dust bacteriaAntimicrobial chemical tied to antibiotic resistance genes in dust

Stop sterilizing your dust

EVANSTON, Ill., USA (December 11, 2018) -- Most people have heard about antibiotic-resistant germs. But how about antibiotic-resistant dust? A new Northwestern University study has found that an antimicrobial chemical called triclosan is abundant in dust -- and linked to changes in its genetic makeup. The result is dust with organisms that could cause an antibiotic-resistant infection.

Infection prevention policies in operating rooms are inconsistent, report shows

New guidance outlines recommendations for infection control in anesthesiology

Arlington, Va., USA (December 11, 2018) -- The Society for Healthcare Epidemiology of America has issued a new expert guidance on how hospitals and healthcare providers may reduce infections associated with anesthesiology procedures and equipment in the operating room. The guidance, published in SHEA's journal, Infection Control & Hospital Epidemiology, recommends steps to improve infection prevention through increased hand hygiene, environmental disinfection, and continuous improvement plans.

Artificial intelligence used to detect signs of ovulation in a woman's saliva automatically and at low cost

Brigham researchers develop smartphone-based ovulation test

Boston, MA, USA (December 11, 2018) - Investigators from Brigham and Women's Hospital are developing an automated, low-cost tool to predict a woman's ovulation and aid in family planning. Capitalizing on advancements in several areas, including microfluidics, artificial intelligence (AI) and the ubiquity of smartphones, the team has built an ovulation testing tool that can automatically detect fern patterns - a marker of ovulation - in a saliva sample. The team evaluated the performance of the device using artificial saliva in the lab and validated results in human saliva samples from six subjects, observing greater than 99 percent accuracy in effectively predicting ovulation. The team's results are published in Lab on a Chip.

Recommending severe patients be evaluated for bronchoscopic lung volume reduction

National Institute for Health and Care Excellence (NICE) issues new guidelines for COPD

REDWOOD CITY, California, USA (December 10, 2018) - Pulmonx, a leader in interventional pulmonary device technology announced today that the National Institute for Health and Care Excellence (NICE) in the UK has expanded its guidance on the diagnosis and management of COPD to include which patients should be referred for evaluation for bronchoscopic lung volume reduction with Zephyr® Endobronchial Valves. The Zephyr Valves offer a minimally-invasive treatment option that has been shown to improve quality of life of emphysema patients by allowing them to breathe easier, be less short of breath, and be more active.

pulmonx

Driver Opioids NStudy examines effects of different opioids on driving performance

(December 5, 2018) - Taking opioids for the treatment of pain has been associated with increased risks of crashing among drivers, but it is unknown whether this applies to all opioids or pertains to specific opioids only. A new British Journal of Clinical Pharmacology study found that the influence of single analgesic doses of methadone and buprenorphine--two different opioids--on driving performance was mild and below the impairment threshold of a blood alcohol concentration of 0.5 mg ml-1.

The Lancet: Harmful, unfounded myths about migration and health have become accepted, used to justify policies of exclusion

  • Stereotypes that migrants are disease carriers who present a risk to public health and are a burden on services are some of the most prevalent and harmful myths about migration.
  • Evidence from a comprehensive new report, including new international data analysis, shows these myths to be unfounded, yet they continue to be used to deny migrants entry, restrict access to healthcare, or detain people unlawfully.
  • Migration benefits national and global economies, and more must be done to counter racism, improve migrants' access to services, and uphold the rights of migrants.
  • Myths about migration and health - including that migrants are disease carriers and are a burden on services - are pervasive and harmful to individuals and society. The normalisation of these myths in popular discourse has allowed governments to introduce hostile and restrictive policies in many countries around the world - including the detention of migrants at US borders, and the denial of treatment to migrants- in the UK's NHS.

 

London, UK (December 5, 2018) - Public health protection and cost savings are often used as reasons to restrict migrants' access to health care, or to deny them entry. Yet, as the new UCL-Lancet Commission on Migration and Health lays out with new international data and analysis, the most common myths about migration and health are not supported by the available evidence and ignore the important contribution of migration to global economies.

anemia detection by smartphoneNo bleeding required:
Anemia detection via smartphone

  • Developed and tested by student with beta-thalassemia

Atlanta, GA, USA (December 4, 2018) - Biomedical engineers have developed a smartphone app for the non-invasive detection of anemia. Instead of a blood test, the app uses photos of someone's fingernails taken on a smartphone to accurately measure how much hemoglobin is in their blood. The results are scheduled for publication in Nature Communications.

Too few fully trained nurses linked to daily 3 percent rise in patient death risk

  • No let-up in risk when headcount boosted with unregistered nursing assistants

London, UK (December 4, 2018) - But plugging the gap with unregistered nursing assistants isn't associated with any diminution in patient harm, suggesting that while these healthcare workers have a key role in maintaining ward safety, "they cannot act as substitutes for [registered nurses]," say the researchers.

One in four patients say they've skimped on insulin because of high cost

New Haven, CT, USA (December 2018) - For patients with diabetes, insulin is a life-saving medicine and an essential component of diabetes management, yet in the past decade alone, the out-of-pocket costs for insulin have doubled in the United States. One-quarter of patients with type 1 or 2 diabetes have reported using less insulin than prescribed due to these high costs, Yale researchers write in JAMA Internal Medicine, and over a third of those patients experiencing cost-related underuse said they never discussed this reality with their provider.