Nursing News

Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 21-24 July 2014

 

London (July 25, 2014) - This page provides an overview of the opinions adopted at the July 2014 meeting of the Committee for Medicinal Products for Human Use (CHMP) and other important outcomes.

Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 23-26 June 2014

 

London (June 27, 2014) - This page provides an overview of the opinions adopted at the June 2014 meeting of the Committee for Medicinal Products for Human Use (CHMP) and other important outcomes.

Bacterial differences found in urine of healthy women and women with overactive bladder

Study debunks common myth that urine is sterile

 

Maywood, IL, USA (May 18, 2014) - Bacteria live in the bladders of healthy women, discrediting the common belief that normal urine is sterile. This finding was presented today by researchers from Loyola University Chicago at the 114th General Meeting of the American Society for Microbiology in Boston.

 

Urine test could help clinicians spot blood clots in at-risk patients

 

San Diego, Cal., USA (May 18, 2014) - A new study by researchers from California and Canada indicates a simple urine test can indicate the presence of venous thromboembolism, a blood clot that has broken free from its point of origin and which travels through the bloodstream, eventually lodging in a vein. The test evaluates the levels of fibrinopeptide B (FPB), a small peptide that's released when a thrombosis forms and which is removed from the body through urine.

 

Prioritized strategies to reduce prevalence of C. difficile in healthcare settings

New expert guidelines aim to focus hospitals' infectious diarrhea prevention efforts

 

Chicago, ILL, USA (May 6, 2014) – With rates of Clostridium difficile (C. difficile) now rivaling drug-resistant Methicillin-resistant Staphylococcus aureus (MRSA) as the most common bacteria to cause healthcare-associated infections, new expert guidance encourages healthcare institutions to implement and prioritize prevention efforts for this infectious diarrhea. The guidelines are published in the June issue of Infection Control and Hospital Epidemiology.

 

Atypical form of Alzheimer's disease may be present in a more widespread number of patients

 

Jacksonville, Fla., USA (May 1, 2014) — Neuroscientists at Mayo Clinic in Florida have defined a subtype of Alzheimer's disease (AD) that they say is neither well recognized nor treated appropriately. The variant, called hippocampal sparing AD, made up 11 percent of the 1,821 AD-confirmed brains examined by Mayo Clinic researchers — suggesting this subtype is relatively widespread in the general population. The Alzheimer's Association estimates that 5.2 million Americans are living with AD. And with nearly half of hippocampal sparing AD patients being misdiagnosed, this could mean that well over 600,000 Americans make up this AD variant, researchers say.

 

Increasing daily coffee consumption may reduce type 2 diabetes risk

 

Boston, MA, USA (April 24, 2014) — People who increased the amount of coffee they drank each day by more than one cup over a four-year period had a 11% lower risk for type 2 diabetes than those who made no changes to their coffee consumption, according to a new study led by Harvard School of Public Health (HSPH) researchers. In addition, the study found that those who decreased their coffee consumption by more than a cup per day increased their type 2 diabetes risk by 17%.

 

EU national authorities and EMA cooperating in response to criminal activities

European Medicines Agency update on stolen vials of Herceptin

 

London, UK (April 17, 2014) - This is an update from the European Medicines Agency on the latest information relating to the stolen vials of Herceptin (trastuzumab) in Italy. The vials, some of which were tampered with, were later re-introduced illegally into the supply chain in some countries.

 

Researchers have identified the point at which hospitals begin to fail, resulting in deaths of critically ill patients

Researchers identify the safety ‘tipping point’ at which hospitals fail

 

Cambridge, UK (March, 17 2014) - The Safety Tipping Point for hospitals occurs when they reach occupancy levels far below 100% according to a new study to be released shortly in US journal Management Science. The three academics involved investigated bed occupancy levels and death tolls in 256 clinical departments of 83 German hospitals during 2004/05 and identified a severe mortality tipping point at 92.5% occupancy.

 

Guidelines on Hyponatraemia have been published

 

Weimar, Germany (March 4, 2014) - Guidelines for diagnosing and treating hyponatraemia, a salt imbalance occurring in up to 30% of hospitalised patients, have recently been published simultaneously in three journals: the full guidelines are available online without charge from "Nephrology, Dialysis and Transplantation", the official Journal of the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA), from the "European Journal of Endocrinology", the official journal of the European Society of Endocrinology (ESE), and also from "Intensive Care Medicine", the official journal of the European Society of Intensive Care Medicine (ESICM). "This underlines the importance and impact of the guideline, which was developed in collaboration between these three societies", explains Prof. Dr. Raymond Vanholder (Ghent, Belgium), president of the ERA-EDTA. The joint guideline group has conducted a strict systematic literature review with the assistance of the Methodological Support Team of European Renal Best Practice (ERBP), the guidance body of ERA-EDTA, to collect the best available evidence on the diagnosis and management of hypotonic hyponatraemia. The new guidelines were developed on this robust basis of evidence.

 

Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 17-20 February 2014

 

Ten new medicines recommended for approval

 

London, UK (February 21, 2014) - The CHMP has recommended granting a paediatric-use marketing authorisation (PUMA) for Hemangiol (propranolol) for the treatment of proliferating infantile haemangioma. This is the second time that the Committee has granted a positive opinion for a PUMA since the introduction of this type of marketing authorisation by the Paediatric Regulation, which came into force in 2007. Please see press release on the website for more information.

 

Popular disinfectants do not kill HPV

 

Penn State, PA USA (February 12, 2014) - Commonly used disinfectants do not kill human papillomavirus (HPV) that makes possible non-sexual transmission of the virus, thus creating a need for hospital policy changes, according to researchers from Penn State College of Medicine and Brigham Young University.

"Because it is difficult to produce infectious HPV particles for research, little has been known about HPV susceptibility to disinfection," said Craig Meyers, Distinguished Professor of Microbiology and Immunology, Penn State College of Medicine.

 

Mindfulness reduces pain and opioid misuse

Mind Over Matter: Beating Pain and Painkillers

 

Salt Lake City, Utah, USA (Feb. 4, 2014) – With nearly one-third of Americans suffering from chronic pain, prescription opioid painkillers have become the leading form of treatment for this debilitating condition. Unfortunately, misuse of prescription opioids can lead to serious side effects—including death by overdose. A new treatment developed by University of Utah researcher Eric Garland has shown to not only lower pain but also decrease prescription opioid misuse among chronic pain patients.

 

Telemedicine Can Reduce Hospitalizations For Nursing Home Residents

 

Lebanon, NH, USA (February 4, 2014)  – Telemedicine used at nursing homes during hours when doctors are not typically present is a viable way to reduce avoidable hospitalizations, according to research published in February’s issue of Health Affairs.

Hospitalizations of nursing home residents are occurring more frequently, and result in complications, morbidity and expensive Medicare costs. When a medical issue arises on nights and weekends that cannot be addressed by the on-call physician not present at the facility, the doctor can either travel to the nursing home or recommend that the resident be sent to the hospital emergency room. Very often, the physician recommends the hospital emergency room.

 

Researchers find blue light exposure may be a countermeasure for fatigue, during the day and night

Blue light may fight fatigue around the clock

 

Boston, MA, USA (February 3, 2014) - Researchers from Brigham and Women's Hospital (BWH) have found that exposure to short wavelength, or blue light, during the biological day directly and immediately improves alertness and performance. These findings are published in the February issue of Sleep. "Our previous research has shown that blue light is able to improve alertness during the night, but our new data demonstrates that these effects also extend to daytime light exposure," said Shadab Rahman, PhD, a researcher in BWH's Division of Sleep Medicine and lead author of this study. "These findings demonstrate that prolonged blue light exposure during the day has an an alerting effect."

 

FDA approves Hetlioz: first treatment for non-24 hour sleep-wake disorder in blind individuals 

 

Silver Spring, MD, USA (January 31, 2014) - The U.S. Food and Drug Administration today approved Hetlioz (tasimelteon), a melatonin receptor agonist, to treat non-24- hour sleep-wake disorder (“non-24”) in totally blind individuals. Non-24 is a chronic circadian rhythm (body clock) disorder in the blind that causes problems with the timing of sleep. This is the first FDA approval of a treatment for the disorder.

 

Columbia University School of Nursing study first to link pay to patient outcomes

China's reliance on lower-paid contract nurses may compromise patient care

 

New York, NY, USA (January 29, 2014) – Economic and health system reforms in China in recent decades have dramatically reduced the number of traditional hospital nursing jobs, known as "bianzhi" or "iron rice bowl" positions, which are guaranteed for life. Instead, more than half of nursing posts in many Chinese hospitals are now filled with contract-based nurses who do the same work as "bianzhi" for lower pay, fewer benefits and limited job security. A new study from Columbia University School of Nursing, published in the journal Human Resources for Health, found significantly higher levels of compensation-related dissatisfaction among contract nurses than their "bianzhi" peers. Hospitals with a disproportionate number of contract nurses also had significantly higher levels of patient dissatisfaction, which prior research has linked to lower quality care and worse outcomes.

 

Caffeine is the most widely used drug, but little is known about helping those who depend on it

Caffeine use disorder: A widespread health problem that needs more attention

 

Washington, D.C., USA (January 28, 2014) - "I'm a zombie without my morning coffee." "My blood type is Diet Coke." "Caffeine isn't a drug, it's a vitamin." Most people make jokes like these about needing a daily boost from their favorite caffeinated beverage—whether first thing in the morning or to prevent the after-lunch slump.

But a recent study coauthored by American University psychology professor Laura Juliano indicates that more people are dependent on caffeine to the point that they suffer withdrawal symptoms and are unable to reduce caffeine consumption even if they have another condition that may be impacted by caffeine—such as a pregnancy, a heart condition, or a bleeding disorder.

 

Sleepy immune system tips balance toward tumors

Fragmented sleep accelerates cancer growth

 

Chicago, ILL., USA (January 27, 2014) - Poor-quality sleep marked by frequent awakenings can speed cancer growth, increase tumor aggressiveness and dampen the immune system's ability to control or eradicate early cancers, according to a new study published online January 21, 2014, in the journal Cancer Research. The study is the first to demonstrate, in an animal model, the direct effects of fragmented sleep on tumor growth and invasiveness, and it points to a biological mechanism that could serve as a potential target for therapy.

 

EMA

Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 20-23 January 2014

 

London, UK (January 24, 2014) - This page provides an overview of the opinions adopted at the January 2014 meeting of the Committee for Medicinal Products for Human Use (CHMP) and other important outcomes.

 

Six new medicines recommended for approval

 

The CHMP recommended granting a marketing authorisation for Eperzan (albiglutide), for the treatment of type 2 diabetes. The Committee gave a positive recommendation for Adempas (riociguat) for the treatment of chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension. Adempas has an  orphan designation. The Committee recommended the granting of a marketing authorisation for Latuda (lurasidone) for the treatment of schizophrenia. The Committee gave a positive recommendation for Bemfola (follitropin alfa), a new biosimilar medicine for the treatment of infertility. Two generic medicines were also recommended for approval by the CHMP: Rivastigmine 3M Health Care Ltd for the treatment of Alzheimer’s dementia and Zoledronic acid Teva Generics for the treatment of osteoporosis and Paget’s disease of the bone.

Anti-Swine Flu Vaccination Linked to Increased Risk of Narcolepsy in Young Adults

 

Stockholm, Sweden (January 21, 2014) - Pandemrix is an influenza vaccination, created in 2009 to combat H1N1, known as Swine Flu. Now, a team of Swedish clinicians testing the vaccine for links to immune-related or neurological diseases have linked Pandemrix to an increased risk of narcolepsy in young adults.

 

PRAC recommends suspending use of Protelos/Osseor

 

  • Recommendation by PRAC to be considered by CHMP for final opinion

 

London, UK (January 10, 2014) - The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has recommended that Protelos/Osseor should no longer be used to treat osteoporosis. In April 2013 the Agency had recommended restricting the use of Protelos/Osseor to reduce the risk of heart problems. These recommendations were the result of a routine benefit-risk assessment and it was also decided at the time that there was a need for a further in-depth review.

 

Prescription opioid abusers prefer to get high on oxycodone and hydrocodone

 

Researchers investigate factors that influence the choice of abused drugs, reports PAIN®

 

Philadelphia (December 2, 2013) – Prescription opioid abuse has reached epidemic levels in the past 15 years. Scientists investigating why people favor one drug over another have found that oxycodone and hydrocodone are the drugs of choice for 75% of opioid-dependent individuals. Their results, published in the current issue of PAIN®, show that oxycodone was the most popular drug overall because of the quality of the high for those who sought such effects. Nonetheless, hydrocodone remains one of the most popular primary drugs, even though it has lower euphoric qualities. In addition, users say they are concerned about acetaminophen poisoning since, until recently, all hydrocodone products contained non-steroidal anti-inflammatory drugs.

 

Vitamin D Decreases Pain in Women with Type 2 Diabetes and Depression

 

Loyola Health Sciences research demonstrates additional benefits of supplement

 

Mayood, Ill., USA (December 2, 2013) – Vitamin D decreases pain in women with type 2 diabetes and depression, according to a study conducted at Loyola University Chicago. These findings were presented at an Oct. 24, 2013 research conference at Loyola’s Health Sciences Campus.

 

Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 18-21 November 2013

 

London, UK (November 22, 2013) - This press release provides an overview of the opinions adopted at the November 2013 meeting of the Committee for Medicinal Products for Human Use (CHMP) and other important outcomes.

 

 

Seven medicines recommended for approval

 

The CHMP recommended granting a marketing authorisation for Sovaldi (sofosbuvir) in combination with other medicines for the treatment of chronic (long-term) hepatitis C in adults. Please see press release for more information.

NICE opens consultation on a new device for managing acute or chronic wounds

 

London, UK (November 14, 2013) - The National Institute for Health and Care Excellence (NICE) today (14 November), starts consulting on its draft medical technology guidance on a device that aims to help improve the treatment of wounds. The draft medical technology guidance supports the case for adopting the Debrisoft monofilament debridement pad as part of the management of acute or chronic wounds in community settings.

 

Neuropace: FDA approves medical device to treat epilepsy. U.S. Food and Drug Administration, 14.11.2013.Neuropace

FDA approves medical device to treat epilepsy

 

Silver Spring, MD, USA (November 14, 2013) - The U.S. Food and Drug Administration today approved a device to help reduce the frequency of seizures in epilepsy patients who have not responded well to medications. The RNS Stimulator consists of a small neurostimulator implanted within the skull under the scalp. The neurostimulator is connected to one or two wires (called electrodes) that are placed where the seizures are suspected to originate within the brain or on the surface of the brain.

 

Touch May Alleviate Existential Fears for People With Low Self-Esteem

 

Washington, DC, USA (November 6, 2013) - As human beings, we all know that we are going to die some day. Most of us deal with this knowledge by trying to live meaningful lives, but people with low self-esteem tend not to see their lives as particularly meaningful. Now, research suggests that touch may help people with low self-esteem in confronting their own mortality.

 

Conversations between lovers about STIs are important in theory but difficult in bed

 

BOSTON, MA, USA (November 6, 2013) - Having sex can be fun; and talking about sex can be fun. Talking about sexually transmitted infections (STI)  with a sexual interest, however, is a totally different matter, according to new research from Indiana University's Center for Sexual Health Promotion.

 

Following simple steps can help reduce surgical-site infections, saving lives and money, says NICE in new standards

 

London, GB (November 1, 2013) - The National Institute for Health and Care Excellence (NICE) has issued standards to help prevent and treat surgical site infection in adults, children and young people undergoing surgical incisions through the skin.

 

Drug is first with breakthrough therapy designation to receive FDA approval

FDA approves Gazyva for chronic lymphocytic leukemia

 

Silver Spring, MD, USA (November 1, 2013) - The U.S. Food and Drug Administration today approved Gazyva (obinutuzumab) for use in combination with chlorambucil to treat patients with previously untreated chronic lymphocytic leukemia (CLL). CLL is a blood and bone marrow disease that usually gets worse slowly. According to the National Cancer Institute, 15,680 Americans will be diagnosed and 4,580 will die from the disease this year.

Better use of lighting in hospital rooms may improve patients' health

 

Cleveland, Ohio, USA (October 30, 2013) - A new study suggests that changing the lighting patterns in hospital rooms so that they're more aligned with normal sleep-wake cycles could help patients feel better with less fatigue and pain. Published early online in the Journal of Advanced Nursing, the findings point to a simple and inexpensive way to potentially improve patient care.

 

Kessler Foundation MS study correlates fMR with negative effect of warmer weather on cognitive status

 

  • Leavitt et al. link fMRI findings with cognitive declines during warmer outdoor temperatures. Results have implications for patients and researchers

 

WEST ORANGE, N.J., USA (October 28, 2013) - Kessler Foundation scientists correlated functional magnetic resonance imaging (fMRI) findings with the negative impact of outdoor temperature on cognitive functioning in multiple sclerosis (MS). This study, “Warmer outdoor temperature is associated  with task-related increased BOLD activation in patients  with multiple sclerosis,” (http://dx.doi.org/10.1007/s11682-013-9267-7) released by Brain Imaging & Behavior as epub ahead of print, corroborates the group’s previous study that established that people with MS performed worse on processing speed and memory tasks during warmer outdoor temperatures versus during cooler outdoor temperatures.

Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 21-24 October 2013

 

London, GB (October 25, 2013) - This press release provides an overview of the opinions adopted at the September 2013 meeting of the Committee for Medicinal Products for Human Use (CHMP) and other important outcomes.

FDA approves second brain imaging drug to help evaluate patients for Alzheimer’s disease, dementia

 

Silver Spring, MD, USA (October 25, 2013) - The U.S. Food and Drug Administration today approved Vizamyl (flutemetamol F 18 injection), a radioactive diagnostic drug for use with positron emission tomography (PET) imaging of the brain in adults being evaluated for Alzheimer's disease (AD) and dementia.

 

Measuring blood sugar with light

 

  • Technology designed in Germany may help people with Type 1 and Type 2 diabetes; described in Review of Scientific Instruments

 

WASHINGTON, D.C., USA (October 25, 2013) - One of the keys to healthful living with Type 1 and Type 2 diabetes is monitoring blood glucose (sugar) levels to ensure they remain at stable levels. People can easily and reliably do this at home using electronic devices that read sugar levels in a tiny drop of blood.

 

Cologne Academic has examined the psychology of physical cleansing

Washing your hands makes you optimistic

 

Cologne, Germany (October 24, 2013) - The Junior Professor for Social and Media Psychology Dr. Kai Kaspar from the University of Cologne has examined how physical cleansing affects us after failure. The result: test subjects who washed their hands after a task were more optimistic than those who did not wash their hands, but it hampered their future performance in the same task domain. The findings of the study were published in the renowned journal Social Psychological and Personality Science. For his experiment, Kaspar took 98 subjects in three groups. In the first part of the experiment, participants from two groups had to solve an impossible task. Both the group who after failing washed their hands as well as the one that did not wash their hands were optimistic that they would do better the second time. The optimism of the group who washed their hands was, however, much greater.

 

Warning of potential side effects of a product can increase its sales

 

Washington, DC, USA (September 24, 2013) - Drug ads often warn of serious side effects, from nausea and bleeding to blindness, even death. New research suggests that, rather than scaring consumers away, these warnings can improve consumers' opinions and increase product sales when there is a delay between seeing the ad and deciding to buy or consume the product.

 

EMA

Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 16-19 September 2013

 

London (September 20, 2013) - This page provides an overview of the opinions adopted at the September 2013 meeting of the Committee for Medicinal Products for Human Use (CHMP) and other important outcomes. This month, the Committee recommended 11 new medicines for approval – the most medicines recommended for approval at a CHMP meeting so far in 2013.

FDA approves Abraxane for late-stage pancreatic cancer

 

Silver Spring, MD, USA (September 6, 2013) - The U.S. Food and Drug Administration today expanded the approved uses of Abraxane (paclitaxel protein-bound particles for injectable suspension, albumin-bound) to treat patients with late-stage (metastatic) pancreatic cancer.

Pancreatic cancer is the fourth leading cause of cancer death in the United States. An estimated 45,220 patients will be diagnosed and 38,460 will die from the disease in 2013, according to the National Cancer Institute. Surgery is the only option to permanently remove or cure pancreatic cancer, but it usually is too late for surgery by the time the cancer is diagnosed.

More than one-third of populations worldwide may have low levels of vitamin D, study shows

 

Nyon, Suisse (September 4, 2013) - New systematic review published in the British Journal of Nutrition analyzes close to 200 population-based vitamin D studies from 44 countries; highest vitamin D values found in North America

A new systematic review published in the British Journal of Nutrition*, is one of the first to focus on patterns of vitamin D status worldwide and in key population subgroups, using continuous values for 25(OH)D to improve comparisons.